Rui Cheng

State Key Laboratory for Conservation and Utilization of Bio-resource

Assistant Professor

       ruicheng@ynu.edu.cn

Education

2019 - 2023​   PhD   Harbin Institute of Technology

2016 - 2019​   M.S.   Northwest A&F University

​2012 - 2016​   B.S.   Shandong Agricultural University

Publications

1. A pan-cancer analysis of alternative splicing of splicing factors in 6904 patients.

Rui Cheng#, Lixing Xiao#, Wenyang Zhou#, Xiyun Jin, Zhaochun Xu, Chang Xu, Pingping Wang, Meng Luo, Mengyun Wang, Kexin Ma, Huimin Cao, Yan Huang, Xiaoyu Lin, Fenglan Pang, Yiqun Li, Qinghua Jiang*

  Oncogene  2021

2. Modification of alternative splicing in bovine somatic cell nuclear transfer embryos using engineered CRISPR-Cas13d.

Rui Cheng#, Xiaoman Zheng#, Yingmei Wang#, Xing Ma#, Xin Liu#, Wenjun Xu, Mengyun Wang, Yuanpeng Gao, Xupeng Xing, Chuan Zhou, Hongzheng Sun, Zekun Guo, Fusheng Quan, Jun Liu*, Song Hua*, Yongsheng Wang*, Yong Zhang* & Xu Liu*

  SCIENCE CHINA Life Sciences  2022

3. Identification of alternative splicing-derived tumor-specific antigens for mRNA vaccine development.

Rui Cheng#, Pingping Wang#, Zhaochun Xu, Huimin Cao, Xiyun Jin, Wenyang Zhou, Meng Luo, Lixing Xiao, Qinghua Jiang*

  Briefings in Bioinformatics  2022

4. Genome-wide analysis of alternative splicing differences between oocyte and zygote.

Rui Cheng#, Xiaoman Zheng#, Yingmei Wang#, Mengyun Wang, Chuan Zhou, Jun Liu, Yong Zhang, Fusheng Quan* and Xu Liu*

 Biology of Reproduction 2020

5. Functional Requirement of Alternative Splicing in Epithelial-Mesenchymal Transition of Pancreatic Circulating Tumor.

Lixing Xiao#, Haoxiu Sun#, Rui Cheng#, Rongrong Yang, Xiyun Jin, Zhaochun Xu, Yideng Cai, Yuexin Yang, Fenglan Pang, Guangfu Xue, Pingping Wang*, Qinghua Jiang*, Huan Nie*

  Molecular Therapy: Nucleic Acid  2024

6. N4-acetylcytidine of Nop2 mRNA is Required to the Transition of Morula-to-Blastocyst.

Mengyun Wang#, Rui Cheng#, Hongjuan He, Zhengbin Han, Qiong Wu*

  Cellular and Molecular Life Science  2023

7. Alternative splicing associated with cancer stemness in kidney renal clear cell carcinoma.

Lixing Xiao #, Guoying Zou #, Rui Cheng #, Pingping Wang, Kexin Ma, Huimin Cao, Wenyang Zhou, Xiyun Jin, Zhaochun Xu, Yan Huang, Xiaoyu Lin, Huan Nie*, Qinghua Jiang*

  BMC Cancer  2021

8. Asymmetric expression of maternal mRNA governs first cell-fate decision.

Yingmei Wang#, Xiaoman Zheng#, Rui Cheng#, Jing Han#, Xing Ma, Wenjun Xu, Lu Gao, Anmin Lei, Jun Liu, Fusheng Quan, Yong Zhang*, Xu Liu*

  Faseb Journal  2021

9. Single-cell transcriptome and TCR profiling reveal activated and expanded T cell populations in Parkinson's disease.

Pingping Wang#, Lifen Yao#, Meng Luo, Wenyang Zhou, Xiyun Jin, Zhaochun Xu, Shi Yan, Yiqun Li, Chang Xu, Rui Cheng, Yan Huang, Xiaoyu Lin, Kexin Ma, Huimin Cao, Hongxin Liu, Guangfu Xue, Fang Han, Huan Nie, Qinghua Jiang*

  Cell Discovery  2021

10. ​​​​​Global characterization of B cell receptor repertoire across COVID-19 patients by single-cell V(D)J sequencing.

Xiyun Jin#, Wenyang Zhou#, Meng Luo#, Pingping Wang, Zhaochun Xu, Kexin Ma, Huimin Cao, Chang Xu, Yan Huang, Rui Cheng, Lixing Xiao, Xiaoyu Lin, Fenglan Pang, Yiqun Li, Huan Nie, Qinghua Jiang*

  Briefings in Bioinformatics  2021

11. ​​​​​Comprehensive analysis of partial methylation domains in colorectal cancer based on single-cell methylation profiles.

Yan Huang#, Pingping Wang#, Wenyang Zhou, Meng Luo, Zhaochun Xu, Rui Cheng, Chang Xu, Xiyun Jin, Yiqun Li, Qinghua Jiang*

  Briefings in Bioinformatics  2021

12. N439K Variant in Spike Protein Alter the Infection Efficiency and Antigenicity of SARS-CoV-2 Based on Molecular Dynamics Simulation.

Wenyang Zhou#, Chang Xu#, Pingping Wang, Meng Luo, Zhaochun Xu, Rui Cheng, Xiyun Jin, Yu Guo, Guangfu Xue, Liran Juan, Anastasia A Anashkina, Huan Nie*, Qinghua Jiang*

  Frontiers in Cell and Developmental Biology  2021

13. ​​​​​Identification and characterization of ERV transcripts in goat embryos.

Ruizhi Deng#, Chengquan Han#, Lu Zhao, Qing Zhang, Beifen Yan, Rui Cheng, Biao Wei, Peng Meng, Tingchao Mao, Yong Zhang, Jun Liu

  Reproduction  2019

14. ​​​​​IL-1β induces increased tight junction permeability in bovine mammary epithelial cells via the IL-1β-ERK1/2-MLCK axis upon blood-milk barrier damage.

Tong Xu, Zhijian Dong, Xixi Wang, Shaopei Qi, Xueru Li, Rui Cheng, Xu Liu, Yong Zhang, Ming-Qing Gao

  J Cell Biochem  2018

15. ​​​​​DeepST: Identification of spatial domains in spatial transcriptomics by deep learning.

Chang Xu#, Xiyun Jin#, Songren Wei#, Pingping Wang, Meng Luo, Zhaochun Xu, Wenyi Yang, Yideng Cai, Lixing Xiao, Xiaoyu Lin, Hongxin Liu, Rui Cheng, Fenglan Pang, Rui Chen, Xi Su, Ying Hu, Guohua Wang, Qinghua Jiang*

  Nucleic Acids Research  2022

16. ​​​​​Global Characterization of Peripheral B Cells in Parkinson's Disease by Single-Cell RNA and BCR Sequencing.

Wang P, Luo M, Zhou W, Jin X, Xu Z, Yan S, Li Y, Xu C, Cheng R, Huang Y, Lin X, Yao L, Nie H, Jiang Q*

  Frontiers in Immunology  2022

17. ​​​​​Identification of shared characteristics in tumor-infiltrating T cells across 15 cancers.

Xiyun Jin, Yideng Cai, Guangfu Xue, Jinhao Que, Rui Cheng, Yuexin Yang, Lixing Xiao, Xiaoyu Lin, Chang Xu, Pingping Wang, Zhaochun Xu, Huan Nie, Qinghua Jiang*

  Molecular Therapy - Nucleic Acids  2023

18. ​​​​​Single-cell transcriptomics reveals the interaction between peripheral CD4+ CTLs and mesencephalic endothelial cells mediated by IFNG in Parkinson's disease.

Shi Yan, Yao Si, Wenyang Zhou, Rui Cheng, Pingping Wang, Di Wang, Wencai Ding, Wanying Shi, Qinghua Jiang*, Fan Yang*, Lifen Yao*

  Computers in Biology And Medicine  2023

19. ​​​​​Alzheimer's Disease Neuroimaging Initiative. Regional transcriptional vulnerability to basal forebrain functional dysconnectivity in mild cognitive impairment patients.

Peng Ren, Wencai Ding, Siyang Li, Guiyou Liu, Meng Luo, Wenyang Zhou, Rui Cheng, Yiqun Li, Pingping Wang, Zhipeng Li, Lifen Yao, Qinghua Jiang*, Xia Liang*

  Neurobiology of Disease  2023